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Description:PotentlyinduceschondrogenesisinMSCs
ChemicalName:2-[((1,1'-Biphenyl)-4-ylamino)carbonyl]benzoicacid
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Potentlyinducesdifferentiationofhumanmesenchymalstemcellsintochondrocytes(EC50=100nM).Reducesdiseaseseverityinamousemodelofosteoarthritis;displaysprotectiveeffectsagainstosteoarthriticstimuliinmaturechondrocytesinvitro.
CompoundLibraries
KartogeninisalsoofferedaspartoftheTocriscreenPlusandTocriscreenStemCellToolbox.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
M.Wt | 317.34 |
Formula | C20H15NO3 |
Storage | Storeat+4°C |
Purity | ≥98%(HPLC) |
CASNumber | 4727-31-5 |
PubChemID | 2826191 |
InChIKey | SLUINPGXGFUMLL-UHFFFAOYSA-N |
Smiles | O=C(NC2=CC=C(C3=CC=CC=C3)C=C2)C1=CC=CC=C1C(O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 31.73 | 100 | |
ethanol | 15.87 | 50 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight317.34.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 3.15mL | 15.76mL | 31.51mL |
5mM | 0.63mL | 3.15mL | 6.3mL |
10mM | 0.32mL | 1.58mL | 3.15mL |
50mM | 0.06mL | 0.32mL | 0.63mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet
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