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Tocris/Kartogenin/4513/50/50 mg
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Tocris/Kartogenin/4513/50/50 mg
品牌 / 
Tocris
货号 / 
4513/50
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4000-520-616
Description:PotentlyinduceschondrogenesisinMSCs
ChemicalName:2-[((1,1'-Biphenyl)-4-ylamino)carbonyl]benzoicacid
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentlyinducesdifferentiationofhumanmesenchymalstemcellsintochondrocytes(EC50=100nM).Reducesdiseaseseverityinamousemodelofosteoarthritis;displaysprotectiveeffectsagainstosteoarthriticstimuliinmaturechondrocytesinvitro.

CompoundLibraries

KartogeninisalsoofferedaspartoftheTocriscreenPlusandTocriscreenStemCellToolbox.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt317.34
FormulaC20H15NO3
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber4727-31-5
PubChemID2826191
InChIKeySLUINPGXGFUMLL-UHFFFAOYSA-N
SmilesO=C(NC2=CC=C(C3=CC=CC=C3)C=C2)C1=CC=CC=C1C(O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO31.73100
ethanol15.8750

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight317.34.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.15mL15.76mL31.51mL
5mM0.63mL3.15mL6.3mL
10mM0.32mL1.58mL3.15mL
50mM0.06mL0.32mL0.63mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet