Product Name | 37,43Gap 27, Connexin MimeticSRPTEKTIFII |
Size | 1 mg |
Catalog # | AS-62642 |
US$ | $79 |
Purity | % Peak Area By HPLC ≥ 95% |
This peptide corresponds to the GAP27 domain of connexin. Connexins, or gap junctions, are a family of structurally-related transmembrane proteins. Gap junctions contain channels that allow the passage of ions and small molecules between adjacent cells. This intercellular communication has been implicated in the coordination of cellular responses to intracellular signaling molecules. Calcium and inositol phosphates are among the second messengers that can pass through gap junction channels. This synthetic connexin-mimetic peptide, Gap 27, was used to evaluate the contribution of gap-junctional communication to osteoclastic bone resorption. It was concluded that gap-junctional communication is necessary for proper bone remodeling. | |
Detailed Information | Material Safety Data Sheets (MSDS) |
Storage | -20°C |
References | Berthoud, V. et al. Am. J. Physiol. Lung Cell Mol. Physiol. 279, 619 (2000); Ilvesaro, J. et al. BMC Musculoskel. Disord. 2, 10 (2001); Chaytor, A. et al. Brit. J. Pharmacol. 144, 108 (2005); Boitano, S. and H. Evans Am. J. Physio.l Lung Cell Mol. Physiol. 279, L623 ( 2000). |
Molecular Weight | 1304.6 |
SRPTEKTIFII | |
Sequence(Three-Letter Code) | H - Ser - Arg - Pro - Thr - Glu - Lys - Thr - Ile - Phe - Ile - Ile - OH |
Product Citations | Yi, FX. et al. (2010). Pregnancy Enhances Sustained Ca2+ Bursts and Endothelial Nitric Oxide Synthase Activation in Ovine Uterine Artery Endothelial Cells Through Increased Connexin 43 Function. Biol Reprod 82, 66. |
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便宜点的就是国产的tiangen,效果会差一点点 如果是大样本的全血 用这个也凑合
根据模板的类型分为DNA类PCR试剂盒和RNA类PCR试剂盒
PCR mix厂家:普洛麦格公司,QIAGEN公司,罗氏公司,TAKARA公司.
成品PCR试剂盒厂家:深圳匹基,上海之江,中山达安,上海科华,上海复星.
2、电泳问题:如果你核酸定量浓度不低的话就考虑电泳问题,电泳的时候加上1kb的marker,如果marker跑不出来说明你凝胶有问题,一般只要marker跑出来了,DNA浓度又比较高,而没有条带这样的现象很少见,DNA提取比较简单而且相当稳定,本人当时做甲基化提取的DNA有一次拿出来电泳忘了放回冰箱了,结果大夏天的在外面放了一天,心怀忐忑的进行了一次电泳,结果条带依然给力,一点都没有降解.
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