Recombinant Human His6-OTUD7B/Cezanne Protein, CF Summary
Product Datasheets
Carrier Free
CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins.Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration.The carrier free version does not contain BSA.
In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard.In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.
E-562
Formulation | X mg/ml (X μM) in 50 mM Hepes pH 7.5, 100 mM NaCl, 1 mM TCEP |
Shipping | The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below. |
Stability & Storage: | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
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Reconstitution Calculator
Background: OTUD7B/Cezanne
OTU domain-containing protein 7B (OTUD7B), also known as cellular zinc finger anti-NF-kappaB (Cezanne), is a C64 type peptidase and a member of the ovarian tumor (OTU) protein super-family with a predicted molecular weight of 93 kDa (1). The human protein shares 90% amino acid sequence identity with its mouse ortholog. Cezanne has been reported to cleave K48-, and K63-linked poly-Ubiquitin chains, and also to display a preference for K11-linked chains (1-3). It has been shown to play a role in the negative regulation of NF-kappa B signaling, possibly by deubiquitination of RIPK1 and TRAF3 (2,4).
- Evans, P.C. et al. (2003) J. Biol. Chem. 278: 23180.
- Enesa, K. et al. (2008) J. Biol. Chem. 283: 7036.
- Bremm, A. et al. (2010) Nat. Struct. Mol. Biol. 17: 939.
- Hu, H. et al. (2013) Nature 494:371.
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硝酸根从根向地上部茎的长距离运输过程中首先要进行木质部的装载。台湾科学家发现NRT1.5是一个低亲和且依赖于pH的双向转运蛋白,位于质膜并在靠近木质部的中柱鞘细胞中表达,对于硝酸根在木质部的装载具有重要作用。
所以NRT1.5是双向性的转运蛋白
另外在八版生理248页第二段,近端小管后半段氯离子通过氯离子碳酸氢根交换体被重吸收,此时小管液中氯离子浓度大于周围组织液氯离子浓度,所以也有细胞旁途径顺浓度被动重吸收,然而资料上的总结和题目里都是说氯离子在近端小管的重吸收为被动重吸收,感觉有些糊涂。希望来个大神指点一二。
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