Oligo Synthesis : CEPs
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2’-OMe-Thiophosphoramidites
2’-OMe-Thiophosphoramidites
Glen Research
| Catalogue No. | Description | Pack Size | Price | Qty |
|
|---|---|---|---|---|---|
| 10-3170-02 | 2"-OMe-A-Thiophosphoramidite | 0.25g | £576.00£547.20Offer until : 31-Mar-2021Offer Code : GLEN5View Offer | Quantity | Add to Order |
| 10-3170-90 | 2"-OMe-A-Thiophosphoramidite | 100umole | £240.00£228.00Offer until : 31-Mar-2021Offer Code : GLEN5View Offer | Quantity | Add to Order |
| 10-3171-02 | 2’-OMe-C-Thiophosphoramidite | 0.25g | £576.00£547.20Offer until : 31-Mar-2021Offer Code : GLEN5View Offer | Quantity | Add to Order |
| 10-3171-90 | 2’-OMe-C-Thiophosphoramidite | 100umole | £240.00£228.00Offer until : 31-Mar-2021Offer Code : GLEN5View Offer | Quantity | Add to Order |
| 10-3172-02 | 2’-OMe-G-Thiophosphoramidite | 0.25g | £576.00£547.20Offer until : 31-Mar-2021Offer Code : GLEN5View Offer | Quantity | Add to Order |
| 10-3172-90 | 2’-OMe-G-Thiophosphoramidite | 100umole | £240.00£228.00Offer until : 31-Mar-2021Offer Code : GLEN5View Offer | Quantity | Add to Order |
| 10-3173-02 | 2’-OMe-U-Thiophosphoramidite | 0.25g | £576.00£547.20Offer until : 31-Mar-2021Offer Code : GLEN5View Offer | Quantity | Add to Order |
| 10-3173-90 | 2’-OMe-U-Thiophosphoramidite | 100umole | £240.00£228.00Offer until : 31-Mar-2021Offer Code : GLEN5View Offer | Quantity | Add to Order |
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2’-OMe-Thiophosphoramidites
2’-OMe-Thiophosphoramidites
Glen Research
2’-OMe-Thiophosphoramidites
The phosphorodithioate linkage (PS2) is both achiral and essentially resistant to nucleases. Previous studies have shown very interesting results which include observations that DNA with PS2 linkages activates RNase H , strongly inhibits human immunodeficiency virus (HIV) reverse transcriptase, induces β-cell proliferation and differentiation, and is completely resistant to hydrolysis by various nucleases. 2"-OMe- RNA Thiophosphoramidites are RNA monomers designed to produce oligos combining the PS2 linkage with the 2"-O-methyl ribose modification. These PS2-modified RNA oligos have potential for use in siRNAs and dithiophosphate aptamers (thioaptamers).
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2’-OMe-Thiophosphoramidites
2’-OMe-Thiophosphoramidites
Glen Research
Glen Report 27.2: introducing 2"-OMe-Thiophosphoramidites
If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200
2’-OMe-Thiophosphoramidites
2’-OMe-Thiophosphoramidites
Glen Research
Diluent: 10% DCM in Acetonitrile
Coupling: See Technical Bulletin
Deprotection: See Technical Bulletin for details (http://www.glenresearch.com/Technical/TB_Thioamidites2015.pdf).
Storage: Storage: Freezer storage, -10 to -30°C, dry
Stability in Solution: Use Immediately
If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200
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